When it comes to comparing rayon vs cotton, both fabrics have their advantages and disadvantages. Rayon is a synthetic fabric made from polyester and rayon fibers. It is lightweight, wrinkle-resistant, and durable, making it a great choice for everyday wear. However, it is not as breathable as cotton and can be uncomfortable in hot weather. Cotton on the other hand is much more breathable and comfortable than rayon but tends to wrinkle easily and needs more care when washing.